Junyu Chen, Ph.D.

Instructor, Russell H. Morgan Department of Radiology and Radiological Science
Johns Hopkins University School of Medicine

I am an Instructor in the Radiological Physics Division of the Russell H. Morgan Department of Radiology and Radiological Science at Johns Hopkins University School of Medicine. My research develops machine learning methods for medical image analysis, with a focus on image registration, segmentation, and denoising across nuclear medicine (PET and SPECT), CT, and MRI.

I work closely with Dr. Yong Du in the Quantitative Imaging Biomarker (QIB) Lab, and with Drs. Aaron Carass and Jerry Prince in the Image Analysis and Communications Lab (IACL) in the Department of Electrical and Computer Engineering. I also maintain an informal affiliation with the KU Lab led by Dr. Katsuyuki “Ken” Taguchi.

I am an active member of the MICCAI Society, where I serve on the committee of the Special Interest Group in Biomedical Image Registration (SIG-BIR) and co-organized the Learn2Reg 2024 and 2025 image registration challenges. Within the Society of Nuclear Medicine and Molecular Imaging (SNMMI), I serve as a non-voting member of the Board of Directors of the Physics, Instrumentation & Data Sciences Council (PIDSC) for a two-year term that began in July 2025.

I received my Ph.D. in Electrical and Computer Engineering from Johns Hopkins University in 2022, advised by Dr. Eric C. Frey, following an M.S.E. from Johns Hopkins (2019) and dual B.Sc. degrees, summa cum laude, in Computer Engineering and Electrical Engineering from North Carolina State University (2017).

Try the registration playground Spatially varying regularization, the method I developed in Medical Image Analysis (2025), running live in your browser via my MIR toolkit: pick two brain MRI slices, drag the hyperparameter sliders, and watch the deformation and the learned regularization map update.
Open

Research interests

  • Medical image registration
  • Image segmentation
  • Image denoising & reconstruction
  • Nuclear medicine imaging (PET, SPECT)
  • Deep learning & machine learning
  • Digital anthropomorphic phantoms

Recognition

Selected publications All publications

Figure from: Beyond the LUMIR challenge: The pathway to foundational registration models
MedIA 2026

Beyond the LUMIR challenge: The pathway to foundational registration models

Junyu Chen, Shuwen Wei, Joel Honkamaa, Pekka Marttinen, Hang Zhang, Min Liu, Yichao Zhou, Zuopeng Tan, Zhuoyuan Wang, Yi Wang, Hongchao Zhou, Shunbo Hu, Yi Zhang, Qian Tao, Lukas Förner, Thomas Wendler, Bailiang Jian, Benedikt Wiestler, Tim Hable, Jin Kim, Dan Ruan, Frederic Madesta, Thilo Sentker, Wiebke Heyer, Lianrui Zuo, Yuwei Dai, Jing Wu, Jerry L. Prince, Harrison Bai, Yong Du, Yihao Liu, Alessa Hering, Reuben Dorent, Lasse Hansen, Mattias P. Heinrich, Aaron Carass

Software & project pages

News

Education

  • Ph.D. in Electrical & Computer Engineering, Johns Hopkins University, 2022
    M.S.E. in Electrical & Computer Engineering, Johns Hopkins University, 2019
  • B.Sc. in Computer Engineering, summa cum laude, North Carolina State University, 2017
    B.Sc. in Electrical Engineering, summa cum laude, North Carolina State University, 2017

Honors & awards

  • 2026 Stanford/Elsevier World's Top 2% Scientists
  • 2024 Forbes 30 Under 30 in Healthcare
  • 2024 Google Cloud faculty research credit
  • 2023 Johns Hopkins Discovery Award
  • 2023 IEEE NSS/MIC/RTSD Trainee Grant
  • 2023, 2024 Gold-level distinguished reviewer, IEEE Transactions on Medical Imaging
  • 2023 Outstanding reviewer, honorable mention, MICCAI
  • 2022 SNMMI Student Research Grant Award (Discovering Molecular Imaging)
  • 2019–2022 Fully funded graduate assistantship, Radiological Physics Division, Johns Hopkins Medical Institutions